•·.·´¯`·.·•PrAcTiCiNgLuCkY4MySaKe•·.·´¯`·.·• ©

Scientists find 'master' breast cancer gene which causes metastasise.

Sat, 15 Mar 2008 01:44:25 GMT

Laughter is still the best medicine.

One round of chemotherapy to go, then my hair grows back YIPPEE!!

That has to be the most devasting part of the whole thing, and I refuse to

wear a wig, so unatural and uncomforable. (Just my opinion)


	by Marlowe Hood Wed Mar 12, 2:14 PM ET PARIS (AFP) - Geneticists have identified a super gene which causes breast cancer to metastasise, the deadly process by which the disease spreads to other organs, according to a study released Wednesday. Described by the US researchers as a "master regulator," the SATB1 gene alters the behaviour of at least 1,000 other genes within tumour cells, said the study, published in the British journal Nature. When over-activated it makes cancer cells proliferate, and when neutralised the gene stops the cells from dividing and migrating, the study reported. "SATB1 will be a remarkable target for cancer therapy," lead scientist Termumi Kohwi-Shigematsu of the Lawrence Berkeley National Laboratory in Berkeley, California, told AFP. The findings could not only pave the way to diagnostic tools that show the likelihood of the disease spreading, she said, but to drugs that could prevent or treat metastasis in breast cancer as well. Up to now, it was impossible to predict whether cancer cells in a tumour were destined to invade neighboring tissue, travel through the blood system and form secondary tumours elsewhere in the body. But the SATB1 protein is just such a marker. A tumour in which it is activated "is destined to metastasise," said Kohwi-Shigematsu. Metastasis is the overwhelming cause of death in patients with solid tumours. Less than 10 percent of women with metastatic breast cancer survive beyond a decade, and just over a quarter make it past five years. SATB1's normal role in organising other genes -- especially related to T-cells that play a critical role in the immune system -- was already well known, thanks in part to pioneering research by Kohwi-Shigematsu in the 1990s. The gene had also been identified in breast tumours. But the new study is the first to establish that "SATB1 is both necessary and sufficient for breast cancer cells to become metastatic," she said. In experiments on mice, Kohwi-Shigematsu and colleagues "knocked down", or deactivated, the SATB1 gene by removing certain RNAs in the tumour cells upon which the gene depends for multiplying. Messenger RNAs are tiny strings of nucleotides -- the basic building blocks of DNA -- that ferry the blueprints for constructing proteins from DNA genes to the cell's ribosomes, the factories where proteins are made. The results, compared to control mice also infected with human metastatic breast cancer cells, were dramatic. Between 125 and 160 metastatic nodules formed in each lung of all the control mice. But in the rodents in which SATB1 was suppressed, the number was between zero and five. Deliberately over-expressing the gene had the opposite effect, causing the cancer cells to rapidly reproduce and run amok. Translating the study's findings into an effective treatment for cancer would require targeting only the tumours in which the SATB1 gene has become overly active. A drug that blocked the gene throughout the body would compromise its critical -- and normal -- role in activating the immune system. Kohwi-Shigematsu is working on a means for delivering an inhibitor via microscopic nanocapsules, and said trials on humans could start within a couple of years. Prognostic tools could be available within a year. Kohwi-Shigematsu's research is part of a new wave of cancer studies focusing on the genetic origins of the disease. Scientists have come to realise, she said, that there are gene expression patterns called prognosis signatures, genetic profiles found across primary tumours that have metastatic potential. "And now we have identified the protein master regulator for metastatis," she said. But the most basic question remains to be answered, she added. "What turns SATB1 on during the course of breast cancer progression? We just don't know." According to the American Cancer Society, about 1.3 million women worldwide are diagnosed each year with breast cancer, and nearly half-a-million succumb to the disease. A little late for some of us, but progress none the less, should my daughter, mother, sisters or neices ever get this disease I believe there will be a cure. Every kind of therapy I have been on since being diagnosed with this Stage four breast cancer has been somewhat new line of therapy and this has kept me going there are medical breakthroughs and more medical breakthroughs which makes things very optimistic for survivors and their families.

Support from MSN spaces is stronger than ever.....

Wed, 30 Jan 2008 23:27:30 GMT

Awwww Marji this is sooo cute, I luv it.

How original and lets HOPE and PRAY for that CURE and NOW!!


	For the past couple of days I have been going through comments and well wishes from everyone and I just want to thank everyone for their tremendous support. I have been on MSN for three years now and the support is still so strong, I have been off for a few months due to health reasons and MSN supporters have never forgotten me. I am very lucky to have such a wonderful support system, and again from the bottom of my heart I want to thank everyone for their kind words and comments, you really keep me going. I truly hope everything is going good for everyone as I have missed you all so much I do plan to stick around and catch up with everyone. Maria, thank you so much for dedicating such a beautiful blog to me. and I mean its just so wonderful it made me feel so special to know I have such wonderful friends on MSN. And Oh that goes for so many of you who never forget me and always leave some comment because you really understand - some of you have been through the same thing. I really appreciate sharing with you, How do you know the truth about Chemotherapy and how wrotten it really makes you feel until you talk to someone who has been through it. There is no way to explain really how it makes you feel, I guess just extremely drained and just plain YUK!!

The Chemo is working -- but it's the Herceptin that is a miracle drug.

Sun, 27 Jan 2008 22:31:01 GMT

I have great news....


	The chemotherapy has taken the cancer from my liver which was very hard to deal with -- this is when the oncologist said my cancer was very serious. It also has good control of the Cancer right now. I will be done with this nasty stuff very soon. I really don't know how I have avoided it until now. As long as it works because it makes you soooo sick. The first type of chemo didn't work and things were progressing while on it, so I had to change to a different type (docetaxol) at that time they added the Herceptin as I am possitive for the her2/neu gene at a 3+ which is the highest and means I am in the 30% of women with Breast Cancer who can recieve this treatment. It use to be used only for the very late stages of your cancer but things are just changing as I go along and now its available before things get to bad to control and the Cancer just takes over. I will be finished at the end of March with the chemo, but I will still be getting the herceptin. My tumour marker tests have been drastically going down finally, my ca15-3 is now 55 and it was 259 when I started on this chemotherapy so things are really lookin up and maybe remission is just around the corner for me, I don't ever loose HOPE that's for sure.

Breast cancer awareness month is every month for me lately

Tue, 02 Oct 2007 16:25:15 GMT

Thanks so much Lesley this tag is perfect for this month and every month.....

October is National
Breast Cancer Awareness Month

Breast Cancer is the most common cancer among Canadian Women

In 2007, an estimated 22,300 women in Canada will be diagnosed with breast cancer. On the average, that is about 429 women diagnosed every week.

In 2007, an estimated 170 men will be diagnosed with breast cancer.

In 2007, an estimated 5,300 women and 50 men will die from breast cancer.

An estimated 162,600 Canadian women who were alive in 2003 had been diagnosed with breast cancer in the previous 15 years.

One in nine (11%) Canadian women is expected to develop breast cancer during her lifetime (this means by age 90), while less than 1% of Canadian men will be diagnosed with breast cancer.
Only one in every 27 Canadian women will die from breast cancer. This means that about two-thirds of the women diagnosed with breast cancer in Canada will live through it. There is more cause to be optimistic. Since 1999, the incidence of breast cancer in Canada has stabilized. As well since the mid- 1980s, the number of people who die from breast cancer has declined steadily. The biggest improvement in survival has been in the 50-69 age group. Higher survival rates have been attributed to improved screening and treatment.
WHAT TO LOOK FOR:
Changes to look for include the following:

Changes to the size or shape of one or both breasts.

Unusual, persistant pain in breast or armpit area.

Swelling under the armpit or below the collarbone.

Nipple changes, including change in the shape or position of a nipple, or a nipple that becomes pulled inward (inverted)

redness

My Second Opinion from Princess Margaret Hospital

Tue, 11 Sep 2007 14:18:46 GMT

My Second Opinion

Well yesterday was the day I had to go

to PMH (Princess Margaret Hospital)

One of Toronto - Ontario's top Cancer

Hospitals.

I found out I am on the right track with my therapy and that is the main

thing here. I am on chemotherapy and the right kind FEC 80/100 and soon to

be changed to another kind and have the Herceptin added, this is what my

oncologist has in mind and this is what they agree on at PMH.

I was so happy to see that everyone is on the same page so to speak.

And by the way I am doing really well on the chemo, my markers continue to

go down and down, which means the cancer is shrinking.

I am on my forth round on Tuesday the 18th of September and then

there will be some changes, things are looking up and I can almost

taste remission its so close.

Knowledge Is Power - Cancer links

Tue, 17 Jul 2007 02:17:27 GMT

Knowledge Is Power

Alliance for Lung Cancer Advocacy, Support and Education - alcase.org
Alliance for Lung Cancer Advocacy, Support and Education - Italian Chapter (ALCASE Italia)
Association of Cancer Online Resources - www.acor.org
Australian Lung Foundation
Breast Cancer Action Saskatchewan - www.bcask.ca
Breast Cancer Network Nova Scotia – www.bca.ns.ca
Canadian Breast Cancer Foundation - cbcf.org
Canadian Breast Cancer Network - www.cbcn.ca
Canadian Breast Cancer Research Alliance
Canadian Cancer Drug Status
Canadian Cancer Society - Canadian Cancer Stats
Canadian Health Network
Canadian Hospice Palliative Care Association – www.chpca.net
Canadian Lung Association
Canadian Policy Research Network - cprn.org
Canadian Prostate Cancer Research Initiative
Canadian Strategy for Cancer Control
Cancer Care – cancercare.org
Cancerconsultants.com - Extensive information on specific cancer sites
CancerDiscussion.com - Public discussions about any type of cancer
Cancerpage.com - Treatment guidelines, news, clinical trials
Cancer Information Guide - Information on most types of cancer
Cancer Information Service - cis.nci.nih.gov
CancerNet - cancernet.nci.nih.gov
CancerNews on the Net - www.cancernews.com
CancerWeb - infoventures.com/cancer
Candlelighters Childhood Cancer Foundation - www.candlelighters.org
CANSIM - online resource for socio-economic statistics
Centers for Disease Control and Prevention
Colorectal Cancer - Research, Treatment, Symptoms & Diagnosis
Colorectal Cancer Association of Canada
Colon Cancer Canada
Cross Cancer Institute
Drug Coverage.ca
Early Prostate Cancer Diagnosis Ontario - www.epcdo.ca
Gilda’s Club - www.gildasclub.org
Gilda's Club, Toronto - www.gildasclubtoronto.org
Global Lung Cancer Coalition
Hereditary Colon Cancer Association
Institute of Cancer Research
Lung Cancer Canada – lungcancercanada.ca
LungCancer.org
Lymphoma Foundation Canada – www.lymphoma.ca
Malecare.com - Prostate, testicular and male breast cancer
National Alliance of Breast Cancer Organizations - www.nabco.org
National Breast Cancer Coalition - www.natlbcc.org
National Center for Complementary and Alternative Medicine - nccam.nih.gov
National Comprehensive Cancer Network - www.nccn.org
National Hospice Organization - www.nho.org
National Ovarian Cancer Organization - www.ovariancanada.org
Ovarian Cancer Canada - www.ovariancancercanada.ca
Partners Against Pain - www.partnersagainstpain.com
PET Scan Information - petscan.ca/petinfo.htm
Procure.ca
Prostate Cancer Research Foundation of Canada
Prostatecentre.com
Prostatecancerfoundation.org - largest philanthropic source of support for prostate cancer research
Real Time Cancer - www.realtimecancer.org
Roy Castle Lung Cancer Foundation
Screening for Colorectal Cancer
Statistics Canada Health Indicators
The American Society of Colon and Rectal Surgeons
The Campaign To Control Cancer - www.cancerforum.ca
The Canadian Women’s Health Network – www.cwhn.ca
The Colon Club
Theprostatecentre.info
Vital Options TeleSupport Cancer Network - www.vitaloptions.org
World Health Organization – www.who.int
Willow Breast Cancer Support and Resource – www.willow.org

Canadian Cancer Agencies

Public Health Agency of Canada Alberta Cancer Board
British Columbia Cancer Agency
BC Wait Times
Canadian Association of Provincial Cancer Agencies - www.capca.ca
Cancer Care Manitoba
Cancer Care Nova Scotia
Cancer Care Ontario
Cancer Care Ontario Wait Times
New Brunswick Atlantic Health Sciences Corporation
Newfoundland Cancer Treatment & Research Foundation
Prince Edward Island - Queen Elizabeth Hospital
Saskatchewan Cancer Agency

Cancer Epidemiology

Cancer Mondial (global) - www-dep.iarc.fr
Cancer Surveillance Online
Surveillance, Epidemiology, and End Results (U.S.) - seer.cancer.gov

Clinical Trials

Cancer Trials - cancertrials.nci.nih.gov
CenterWatch Drugs in Clinical Trials Database
My Health Canada - Canadian Clinical Trials Directory
National Cancer Institute of Canada - Clinical Trials Group
Ontario Cancer Trials - ontariocancertrials.ca
Open Clinical Trials: BC Cancer Agency

Contact Your Federal MP and Provincial MPP

Federal MPs

Alberta Legislature
British Columbia Legislature
Manitoba Legislature
New Brunswick Legislature
Newfoundland House of Assembly
Northwest Territories Legislature
Nova Scotia Legislature
Nunavut Legislature
Ontario Legislature
Prince Edward Island Legislature
Quebec Legislature
Saskatchewan Legislature
Yukon Legislature

En Francais

Centre d'oncologie Ville Marie
Fédération nationale des centres de lutte contre le cancer - www.fnclcc.fr
Institut Curie - www.curie.fr
Institut Gustave Roussy - www.igr.fr
Institut Pasteur - www.pasteur.fr
La Ligue Nationale Contre le Cancer
Réseau uébécois pour la Santé du Sein - www.rqss.qc.ca
Urolink Laboratoire Cassenne - www.urolink.fr

Health Ministries

Health Canada

Alberta
British Columbia
Manitoba
New Brunswick
Newfoundland
Northwest Territories
Nova Scotia
Nunavut
Ontario
Prince Edward Island
Quebec
Saskatchewan
Yukon

International

American Cancer Society - www.cancer.org
American College of Surgeons
American Institute for Cancer Research – aicr.org
American Society of Clinical Oncology - www.asco.org
Cancer Index – a guide to internet resources for cancer – cancerindex.org
Cancer Literature – cancer.gov
Cancer Net (Deutsch/Espanol) - www.meb.uni-bonn.de/cancernet
Cancer Research Foundation of America
Cancer Research UK - cancerresearchuk.org
CancerBackup - www.cancerbackup.org.uk
Cancercare.org - US social service agency providing services to cancer patients and families
Europa Donna - www.cancereurope.org
European Institute of Women's Health/Women's Cancer Information Project
European Oncology Nursing Society
European Society for Medical Oncology - www.esmo.org
European Women's Cancer Information Project - www.eurohealth.ie/cancom
Federation of European Cancer Societies - www.fecs.be
International Agency for Research on Cancer
Int. Committee for Establishment and Development of Oncology Centers
International Union Against Cancer/Union Internationale Contre le Cancer
Karolinska Guide: a general guide to the web regarding diseases

Lance Armstrong Foundation - www.LAF.org
Lymphoma Research Foundation of America - www.lymphoma.org
Mayo Clinic Cancer Resource Center - www.mayohealth.org
National Comprehensive Cancer Network – nccn.org
National Institutes of Health Library and Literature Resources
North American Association of Central Cancer Registeries
Nutrition Action: practical up to date guide to healthy living
Oncolink.org - University of Pennsylvania cancer web site
Ons.org - US Oncology Nursing Society
Pan-American Health Organization - www.paho.org
Patientadvocate.org- US based national health advocacy organization
Physician Data Query: summaries for patients/health professionals

PubMed Central – A free archive of life sciences journals
Spanish Association Against Cancer
UK Department of Health
US TOO International - www.ustoo.com
West Japan Thoracic Oncology Group
World Health Organization Health for All Database - www.who.dk

Medical Journals

American Journal of Clinical Oncology - www.amjclinicaloncology.com
Canadian Journal of Oncology – articles from the National Library of Medicine database
Canadian Medical Association Journal - cmaj.ca
Cancer Detection and Prevention - www.cancerprev.org
Cancer Letters - www.cancerletter.com
Journal of the National Cancer Institute - www.jnci.oupjournals.org
Lancet - UK medical journal
New England Journal of Medicine
Springer Index of Oncology Journals

Professional Links

Association of Oncology Social Work - www.aosw.org
Canadian Association of Medical Oncologists - www.cos.ca
Canadian Association of Medical Radiation Technologists - www.camrt.ca
Canadian Association of Nurses in Oncology - www.cos.ca/cano/web/en
Canadian Association of Radiation Oncologists – www.caro-acro.ca
Canadian Medical Association – www.cma.ca
Canadian Oncology Societies
Oncology Nursing Society - www.ons.org
Oncology.com - www.oncology.com

Research Organizations

American Association for Cancer Research - www.aacr.org
Canadian Health Services Research
Canadian Institute for Health Information
Canadian Institutes of Health Research
Cancer Genome Anatomy Project - www.ncbi.nlm.nih.gov/CGAP
Cancer Research Institute - www.cancerresearch.org
European Association for Cancer Research - www.eacr.org
European Organization for Research and Treatment of Cancer - www.eortc.be
International Agency on Cancer Research - www.iarc.fr
National Cancer Center (Japan) - ncc.go.jp
National Cancer Institute of Canada
The Terry Fox Foundation – www.terryfoxrun.org

Tobacco Control

Action on Smoking and Health – ash.org.uk
Canadian Council for Tobacco Control - www.cctc.ca
Canadian Respiratory Health Professionals
Canadian Tobacco Control Research Initiative
Canadian Tobacco Control Research Summit
Cancer Care Nova Scotia: Tobacco Control
Coalition for World No-Tobacco Day - www.wntd.com
Early Detection Trial for Current and Former Smokers
Go smokefree! Health Canada Tobacco Control Programme
International Non-Governmental Coalition Against Tobacco - www.ingcat.org
Ontario Campaign for Action on Tobacco
Organizations Working in Tobacco Control
Stupid.ca – www.stupid.ca
Tobacco Control Advocacy
Tobacco Control In Canada
WHO Tobacco Free Initiative - www.who.int/toh

These are all from The Cancer Advocacy Coatition of Canada

http://www.canceradvocacy.ca/

Canadian Cancer Statistics for 2007

April 11, 2007: Canadian Cancer Statistics 2007

April 11, 2007: Canadian Cancer Statistics 2007: Breast Cancer Death Rate Dropping

Chemo's got me down, But I'm getting back up - it's working it's magic thank god....

Wed, 11 Jul 2007 17:51:08 GMT

I have managed to stay away from chemotherapy for eleven years dealing with a breast cancer diagnoses, then to have my cancer change from a stage 0 DCIS (ductal carinoma in situ) to a stage VI mestastic cancer that there is only control for now.

But in the past couple of months I have also found out that I am also Her 2/neu positive (meaning my cancer is more aggressive) only 30% of women have this and are eligible for a little more help from a different class of drug called smart drugs like Herceptin to slow it down some.

My cancer has now progressed to the liver with tumours that have to be shrunk there, also there are swollen lymph nodes and all this came about so fast, I haven't had to deal with this toxic/brutal medication - Doesn't mean I haven't given it alot of thought - I knew one day I would have to have it because I would need it just didn't know when?

That time is here and it's been a rough one I will tell you that much I am not here to candy coat it I couldn't if I tried.

But also it's nothing I can't handle because I have to. Really what else can I do? The stuff makes you so sick and you have no choice but to count down till the next time you get it because every day is 7 days post chemo or 3 days post chemo, and so forth not just another day, they all mean something In the way your handling your chemotherapy. If your feeling fine then great but chances are there is some small thing wrong you think but its not so small, it can turn into weeks in the hospital fast. I wonder if you EVER get use to It? I doubt that very much?

Well I am happy to say six days in the hospital and two nights in ER and my two rounds of chemotherapy have paid off, my tumour markers have already dipped down almost 100 pts. from 275 to 189.

I was so happy to hear that I didn't know what to do and no more getting sick that part is under control too. Things are looking up.

I still have a second opinion coming up with the big city hospital Princess Margaret I have to double check that they are giving me the right stuff and at the right time and about the Herceptin should I be recieving it NOW or Later? It's always good to double check and get your second opinion when things change so drastically with your health and your therapy, well this is the second time my therapy has changed that is also why I am just making sure. I started with Princess Margaret so I do have a very good dr. down there I always check with. Just a precaution it is my life we are talking about here.

Chemotherapy - the art of giving just enough medicine to kill the

cancer and not you.......

Yeah I am back and once I figure

out how this MSN works again

I will be updating - lots to catch up

on and I so look forward to seeing what

everyone else has been up to

and thanks for all your well

wishes they are greatly appreciated

Always the greatest Support here on

MSN SPACES.

Look Both Ways Men Do Get Breast Cancer Too

Wed, 14 Mar 2007 20:02:48 GMT

Just my way of saying that
"Men Get Breast Cancer Too!"
Please pass this page along to your friends and family!
Males are no different they have breast tissue therefore, if you should feel any changes in your breasts, anything at all, lumps, bumps puckerness, anything.
"When in doubt, CHECK IT OUT"
Cancer does not discriminate it chooses no one, it just happens and most doctors have no reasons why it did happen to us.
One day you are fine and the next you are starring death in the face so it seems, but cancer is no longer a death sentence and it has no PREDJUDICES whatsoever. It doesn't care who it chooses young or old, rich or poor, male or female, black or white, it just doesn't matter everyone is prone to this disease.
We are living with Cancer longer and longer thanks to medical breakthroughs through cancer research and lots of cancer money being raised through a lot of fundraising and people always giving to Cancer because everyone has been touched in some way there was a time that Cancer was a death sentence but not these days and WE are living longer and longer with Cancer each day through modern medicine and breakthroughs happening daily in the medical oncology field. One day there will be a cure for cancer.

John W. Nick Foundation, Inc.

Created November 9, 1995 in memory of
John W. Nick who died from breast cancer
June 11, 1991 at the age of 58.

A non-profit organization focused on educating
the public about the dangers of
male breast cancer.

http://www.johnwnickfoundation.org/index.html
a very informative website for men
diagnosed with breast cancer or interested in
breast cancer prevention.

This poem was written by a man from New York.
With his permission I would like to share it with you.
Masquerade
I see my struggle when I look in the mirror
At my body, sore and tender
Yet another dose of reality making it all seem clearer
My strength tested for as long as I can remember
I rely on my strong sense of pride
And with my head held high and proud
I challenge this journey with mighty stride
To escape the curse of this painful shroud
As time goes on we hold fast to our stand
With our voices soaring high
The end of this masquerade is close at hand
Our fight continues-another day going by
It doesn't discriminate so I'm as strong as I can
The silence is over from your fellow Man.
(This poem is dedicated to all the quiet stories of men who suffer from Breast Cancer.
The silent victims of this horrific disease need not be ashamed or emasculated,

but rather stand united on the front to eradicate Breast Cancer with our more recognized fighters.)

You may print the information on this website as long as credit is given to John W. Nick Foundation. Inc

Information on this web site is not intended to provide or diagnose male breast cancer or any other medical condition.

If you feel something is wrong, please see your health care provider for complete diagnosis and treatment

I am on top of the world - Happy St. Patrick's Day

Wed, 14 Mar 2007 20:02:17 GMT

My LUCKY DAY I like to think but it's all a state of mind.

(and It is my lucky day lol)

Well it's been along time between updates due to the pc problems but just know that mine is on its way to my house right this minute, its in town I just don't know when they will be bringing it to the door. I am too excited I will be so happy to see it, but they I have to set up again and take the crap out ( pre-installed software that I am never going to ever use) like have you ever ordered a movie online from block buster? Not when the store is cross the street I am not going to sit here and wait for them to deliver a movie and then there's the whole thing about giving credit card info on the internet I am just not doing it ever. Under NO Curcumstances That is my NO. 1 rule.

Anyways I have done this setup so many times I do plan to be up and running in a matter of a day or two, but this time I was thinking of actually getting a professional to take this stuff out incase I am doing it wrong all though I am following instructions from HP some of them I do believe don't even own a computer I swear but I am not getting started on HP and guess what again it doesn't say in the email what they even did to my pc.

Surprised NA!

It's coming home and that's the main thing and then I am getting Photoshop installed that's right you read it right, I cherl aka practicinglucky4mysake am going to learn psp you read it here first. This weekend coming John has promised to take me and get this program installed in a new block of memory so it doesn't interferr with my other stuff on my pc and I can do this stuff offline when I want to Yipee.

For now I have this little program called "Print Shop" it cost a whole $9 but it will make a birthday card and frame a picture and do quite a bit so I have to wonder are you just paying for the name.

A Blarney Stone from Jean thanks a bunch Jean

Lookin Kinda Kool there Carlos thanks for the Pic have a good St Paddys Day and have a green beer for me.

Your Lookin Good ~M~ thanks a bunch

Oh I Like this one Corona Gurl its a winner in my books got that magic word

LUCKY lol, thanks for stoppin by and hope the new job is everything and more.

And Jean again -- she has Photoshop so she doesn't require sleep

anymore lol. Thanks for all the teddy bears and goodies you have made me

I luv them all.

2007

Please sign my map/guestbook everyone has these things wow!

Thu, 01 Mar 2007 20:34:13 GMT

I wish I could make it around to old friends and new ones I am gonna try it

Sun, 25 Feb 2007 05:37:28 GMT

So tired of PC problems, HP replaced the PC it wasn't me....

I have no idea what day that is lol, but I will see what I can do ON THIS OLD BEATER OF MINE

to do this thing, I promise I will, my computer is gone back to HP once again and they have still not agreed to replace it they are replacing the hard drive this time, I will have all new insides but they insist on not replacing my lemon of a computer -- I will never ever buy HP again never in my life, and then they keep telling me: I have 14 days now left on my warranty well I have my reciept and know how long I have been doing non- stop system recoveries and its been since April 13, 2006 and that's just a little more than 14 days but right at this time when my pc is really acting up I need those extra days what am I going to pay extra money for an extended warranty for?? because I have really gotten to know the HP techs at the call center -- do you know how hard it is to get the same one twice and I managed to get the same guy twice I joked with him and told him I am stalking him until I get this pc fixed or better still replaced.

I have gone way above and beyond what I am suppose to do as a customer and know they just want to sent me these parts on my credit card and then I install them and when they recieve they old parts reinburse me on my credit card what kind of customer satisfaction is that?? what if I was some old lady who knew nothing about computers like I did, I didn't know how to turn it on and now its been sleepless nights with google my buddy trying to figure out what was wrong with that pc, because it just wouldn't give an error code. gr.......

Now its gone again and I am without again and when its here its sooo much stress with the stupid thing

I dread it. I don't enjoy it like I use to and that's not fair --I told them this time fix it I am not any more that is your job not mine its too stressful for me to continue doing it. I don't believe they actually listened and just benched it, but it was at the point where nobody could add to my file but the case manager and she had to make a final decision and this is it, new hard drive.

I hope it works -- I better not have any more problems now with it because the difference now is I have her fax no. I am not going through the call center I am going directly to her if I do have any further problems enough is more than enough I have put up with. And I cringe every time they say "thank you for your patients" if they only knew I am not patient. not anymore.

I will try to get on this old one but for some reason it won't leave comments I will figure that one out lol,

already problems with this one lol but this one is very reliable I started on this one and I should have just

invested some money into it instead of buying a brand new one I could kick my butt, be careful what you wish for

wow, did I learn a hard lesson with that darn PC.

I hate it. And when I bought it I just luved it.

It is really nice and fast when it worked on those rare occasions.

Honestly I had to send it away lmao.......

This solves a Little mystery for me there are two Bebe's

Thank you ღ-»вєвє«-ღ for this beauty image.

I thought I was going a little crazy there for awhile.

Sorry Bebe for the mix up. I told you I thought there might

be another person with the same name. lol. So FUNNY NOW.

The Secret - Has anyone seen the secret?

Tue, 20 Feb 2007 01:35:04 GMT

Jean! you have come along way baby, Look at this beauty, I just luv it.

Honestly you would Never know its only been six weeks you

have had that program--never. You know I just luv those

cuddly, comforting teddy bears, thanks so much Jean.

And the work on your space is amazing you go girl your doing Super.

This is so true Cathy thanks a bunch -- "Party Princess"

I just loved it when I read it cause you don't know how

many times I get out of bed and go online to be nosey lol.

So here you go I pass this one to everyone - ya the lazy way hehe.

I am waiting on HP supervisor about my pc it is really acting

up still and my year warranty is almost up OH NO!

yeah a whole year of stress and 21 system recoveries and

I am nowhere with it, it doesn't go for more than a week now.

I told someone just the other day
That I had friends all over the place
They wondered how I could say I knew
Someone I hadn't met face to face

We write little notes and send out sites
And a few write just to say "Hey"
Then I have a few special ones
That I talk to every single day

At times when I can't sleep at night
I will often go online
There I will find a friend or two
That will help me pass the time

I think sometimes my online friends
Know me more than my neighbors next door
And they don't care if my house is clean
Or what time I came in the night before

So no matter how far apart you are
If you're sincere in the love that you give
Online friends can be as true and as real
As your friends in the place where you live

_____♥♥♥♥♥♥________ ♥♥♥♥♥♥________
____♥♥♥♥♥♥♥♥♥♥___♥♥♥♥♥♥♥♥♥♥______
____♥♥♥♥♥♥♥♥♥♥♥♥_♥♥♥♥♥♥♥♥♥♥♥_____
____♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥_____
_____♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥______
______♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥______
_______♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥_______
________♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥♥________
__________♥♥♥♥♥♥♥♥♥♥♥♥_________
____________♥♥♥♥♥♥♥♥♥____________
_____________♥♥♥♥♥♥♥______________
_______________♥♥♥________________
________________♥_________________

A Friend is sending some Love your way,
send this to your friends you hold Dear, and even
to the friend who sent it to you!
hugs~cathy~

________________________________________________________________________________________________________________________________

Lots of Luck to Gaylene and Xena and David down

there at the s.h.o.f. there was a few familiar names down

there for this one. I don't really like when its like that I

really would rather not vote, but the way its set up this

time I was able to vote for everyone lmao.

Thank god, good luck guys.

______________________________________________________________________________________________________________________________________________

"The Secret" is the way you think,

The way you think can change your life,

The way you have been thinking is what has

made your life what it is, this is what they

say is "the secret".

from what I understand.

Change your way of thinking and you can change your way of life.

People have been talking about "the secret" on Oprah and other

repected talk shows, have you seen/heard the secret DVD?

I have and it's changed my way of thinking.

To order the Secret On-line movie or to visit the website

click the picture see what everyone is talking about.

What is The Secret?

After being featured on The Ellen DeGeneres Show in fall 2006, millions of people want to know and have helped make the book a bestseller, and due to popular demand, have helped make the DVD available in Canada in January. An audio edition is also available.

In The Secret, scientists, inventors, psychologists, business people, doctors, theologians, and economists -- all regular people who have gained insight about this profound yet simple secret -- share their insight. The book and DVD also illustrate this powerful knowledge through stories of everyday people like "Miracle Man" Morris Goodman and how he recovered from paralysis using The Secret. Best-selling authors and philosophers including Jack Canfield, Bob Proctor, John Assaraf, Dr. John Gray and Joe Vitale offer advice on how to practice The Secret in your life.

Watch four exciting trailers for and an audio excerpt from The Secret.

Trailer #1 [Duration: 1:59]
Trailer #2 [Duration 2:23]
Trailer #3 [Duration :57]
Trailer #4 [Duration 1:00]
Listen to an audio excerpt [Duration: 10:00].

Please note that the clips may take a few seconds to download.

Order your copy of The Secret book, DVD and audio edition today

this is from the secret website and chapters click there for more information, give some of those trailers a listen I have seen the dvd and its quite interesting how this can work.